Lead Information Systems Engineer Salary in San Francisco, CA.
Updated on: Jan 14, 2026
How much does a Lead Information Systems Engineer make in San Francisco, CA?
The average Lead Information Systems Engineer in San Francisco, CA makes $183,514,
72% above the national average Lead Information Systems Engineer salary of $106,730.
This pay is 33% greater than the combined average salaries of other metroes San Jose, CA, Milwaukee, WI, and Boston, MA.
Read more
Lead Information Systems Engineer Salary Average
Compare salary averages by location
Explore and compare salaries based on different locations to gain valuable insights and make informed decisions.

See salaries for related job titles
*Data is estimated and depends on the generous anonymous contributions of individuals