Lead Information Systems Engineer Salary in San Francisco, CA.
Updated on: Jun 17, 2026
How much does a Lead Information Systems Engineer make in San Francisco, CA?
The average Lead Information Systems Engineer in San Francisco, CA makes $183,541,
72% above the national average Lead Information Systems Engineer salary of $106,746.
This pay is 31% greater than the combined average salaries of other metroes San Jose, CA, Seattle, WA, and Jacksonville, FL.
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Lead Information Systems Engineer Salary Average
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*Data is estimated and depends on the generous anonymous contributions of individuals