Professional Registered Nurse Salary in San Francisco, CA.
Updated on: May 20, 2026
How much does a Professional Registered Nurse make in San Francisco, CA?
The average Professional Registered Nurse in San Francisco, CA makes $255,609,
72% above the national average Professional Registered Nurse salary of $148,660.
This pay is 48% greater than the combined average salaries of other metroes San Jose, CA, Oklahoma City, OK, and Louisville, KY.
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Professional Registered Nurse Salary Average
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*Data is estimated and depends on the generous anonymous contributions of individuals