Senior Instrumentation Engineer Salary in San Francisco, CA.
Updated on: Feb 4, 2026
How much does a Senior Instrumentation Engineer make in San Francisco, CA?
The average Senior Instrumentation Engineer in San Francisco, CA makes $138,798,
72% above the national average Senior Instrumentation Engineer salary of $80,724.
This pay is 45% greater than the combined average salaries of other metroes San Jose, CA, Phoenix, AZ, and Virginia Beach, VA.
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Senior Instrumentation Engineer Salary Average
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*Data is estimated and depends on the generous anonymous contributions of individuals