Senior Multi-discipline Systems Engineer Salary in San Francisco, CA.
Updated on: May 20, 2026
How much does a Senior Multi-discipline Systems Engineer make in San Francisco, CA?
The average Senior Multi-discipline Systems Engineer in San Francisco, CA makes $245,066,
72% above the national average Senior Multi-discipline Systems Engineer salary of $142,528.
This pay is 31% greater than the combined average salaries of other metroes San Jose, CA, Colorado Springs, CO, and Boston, MA.
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Senior Multi-discipline Systems Engineer Salary Average
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*Data is estimated and depends on the generous anonymous contributions of individuals