Senior Staff Nurse Salary in San Francisco, CA.
Updated on: May 27, 2026
How much does a Senior Staff Nurse make in San Francisco, CA?
The average Senior Staff Nurse in San Francisco, CA makes $194,270,
72% above the national average Senior Staff Nurse salary of $112,986.
This pay is 43% greater than the combined average salaries of other metroes San Jose, CA, Atlanta, GA, and Dallas, TX.
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Senior Staff Nurse Salary Average
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*Data is estimated and depends on the generous anonymous contributions of individuals