Staff Nurse Salary in San Diego, CA.
Updated on: Apr 29, 2026
How much does a Staff Nurse make in San Diego, CA?
The average Staff Nurse in San Diego, CA makes $133,829,
33% above the national average Staff Nurse salary of $100,292.
This pay is 12% greater than the combined average salaries of other metroes San Jose, CA, Charlottesville, VA, and Columbus, OH.
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Staff Nurse Salary Average
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*Data is estimated and depends on the generous anonymous contributions of individuals