Dr. David Apelian, M.D., Ph.D., MBA,was the Chief Medical Officer and Executive Vice President of Achillion Pharmaceuticals, Inc. since May 28, 2013 until December 28, 2017. Dr. Apelian leads the Achillion rare disease development program for novel small-molecule complement factor D inhibitors for alternative pathway-mediated diseases. He was responsible for creating portfolio strategy and managing the Achillion 's clinical development programs with a focus on hepatitis C. He was instrumental in securing a partnership between Achillion and J&J, which resulted in a $225 million equity upfront payment and the potential for over $900 million in milestones. His clinical development and regulatory experience spans 17 years in all phases of development ranging from discovery to registration, across multiple therapeutic areas including GI, hepatology, immuno-oncology infectious diseases and rare diseases. He served as Chief Medical Officer at GlobeImmune, Inc. since January 2005 until 2013. He served as the Senior Vice President of Research & Development at GlobeImmune, Inc. since December 2008. He was responsible for clinical development, regulatory affairs, clinical immunology, development of companion diagnostics, as well as target discovery and preclinical research. He served as Vice President of Clinical Development and Regulatory Affairs at GlobeImmune, Inc. from January 2005 to December 2008. Dr. Apelian joined GlobeImmune from Bristol-Myers Squibb, where he served as a Clinical Director in the Department of Clinical Design and Evaluation/Infectious Diseases Group and was Medical Leader for clinical development for the NDA filing of entecavir for chronic HBV. Prior to, he served as Clinical Director in the Department of Hepatology/Gastroenterology at Schering Plough, coordinating a supplemental NDA filing for interferon alpha-2b and ribavirin for the treatment of pediatric patients with chronic hepatitis C viral infection (HCV). He has been Director of Eiger BioPharmaceuticals, Inc. since June 14, 2017. He completed residency training in pediatrics at New York Hospital, Cornell Medical Center and is board certified in Pediatrics. Dr. Apelian received his Ph.D. in Biochemistry from Rutgers University, his M.D. from the University of Medicine and Dentistry of New Jersey and an M.B.A. from Quinnipiac University. He earned a B.A. in Biochemistry from Rutgers University.