Dr. Jay R. Venkatesan, Ph.D., M.D. has been the President of Alpine Immune Sciences, Inc since June 2016. Dr. Venkatesan has been a Managing Partner at Alpine BioVentures, GP, LLC since July 13, 2015. He served as the President of Nivalis Therapeutics, Inc. since July 24, 2017. Dr. Venkatesan was the Co-Founder and served as Chief Executive Officer of Alpine Biosciences, Inc. from November 2015 to June 2016. He served as Chief Executive Officer at Alpine Immune Sciences, Inc. from November 2015 to June 2016. Dr. Venkatesan served as an Executive Vice President and General Manager of Cascadian Therapeutics, Inc. (formerly Oncothyreon Inc.) from August 11, 2014 to May 15, 2015. Previously, Dr. Venkatesan was the Founder and served as Portfolio Manager and Managing Director of Ayer Capital Management LP, a global healthcare equity fund from 2008 to December 2013. He served as an Analyst at Apax partners and McKinsey & Co. He founded Varro Technologies and served as its Chief Executive Officer. From July 1995 to August 1996, he served at Partricof & Co. Ventures, with a focus on life sciences investments and healthcare venture investing. Dr. Venkatesan leads the creation of new companies, identifies investment opportunities and collaborates with innovators to develop game-changing therapies that can meaningfully impact patients??? lives. He served at McKinsey & Company from August 1993 to June 1995, where he consulted companies in the pharmaceutical, media and information technology industries. He has been an Independent Director of Iovance Biotherapeutics, Inc. (formerly Lion Biotechnologies, Inc.) since September 3, 2013. He has been a Director at Alpine Immune Sciences, Inc. since June 13, 2016. He has been a Director at Exicure Inc. since March 2014. He serves on the board of CellBioTherapy, Transplant Genomics, Exicure Therapeutics, AuraSense Therapeutics. He serves as a Director of Bain Capital, LLC and Brookside Capital Management, LLC. He served as a Director of Nivalis Therapeutics, Inc. since July 24, 2017. He served as a Director of Brookside Capital Partners since July 2002 until 2007. He served as a Director of REVA Medical, Inc. He served as a Director of Targanta Therapeutics, Corp. from January 2007 to August 25, 2008. Dr. Venkatesan holds an M.D. from the University Of Pennsylvania School Of Medicine, an M.B.A. from the Wharton School of the University of Pennsylvania and has received a B.A. in Chemistry from Williams College, where he was elected to Phi Beta Kappa.