Dr. Michael E. Lewis, Ph.D., co-founded Cara Therapeutics, Inc. and has been its Chief Scientific Advisor since September 2004. Dr. Lewis served as Secretary at Cara Therapeutics Inc. Dr. LewisDr. Lewis has been the President of BioDiligence Partners, Inc. since 1994. Dr. Lewis has more than 30 years of scientific experience in academic, government laboratories, several major pharmaceutical and also in bio-technology companies. He co-founded Arena Pharmaceuticals, Inc. in 1997 and served as its Chief Scientific Advisor from 1997 to 2003. He also co-founded Adolor Corporation in 1994 and served as its Chief Scientific Advisor from 1994 to 1997 and also participated on their analgesics development team and assisted in pre-IPO financing and corporate partnering presentations. Dr. Lewis served as a Vice President of Research for Symphony Pharmaceuticals from 1993 to 1994. He co-founded Cephalon, Inc., where he served as Senior Scientist, Director of Pharmacology and Senior Director of Scientific Affairs, from 1988 to 1993. Prior to that, he supervised as a Principal Investigator of E. I. DuPont de Nemours & Co., Inc. from 1985 to 1987. Prior to that, about five years of experience in opioid research at the National Institutes of Health and the University of Michigan. He served as a Director at Cara Therapeutics, Inc. since September 2004 until July 2010. He served as an Independent Director of PolyMedix, Inc., since November 2005 until March 29, 2013. Dr. Lewis served as a Director of Aeolus Pharmaceuticals Inc. (formerly Incara Pharmaceuticals Corp.) from June 2004 to May 2013. He served as a Director of PolyMedix Pharmaceuticals Inc. He served as a Pre-IPO Director of Arena Pharmaceuticals Inc. from 1997 to 2000. He is an inventor or co-inventor on 15 issued U.S. patents and is an author or co-author of over 40 publications on opioids, including journal articles, invited reviews and book chapters. Dr. Lewis participated in pre- and post-IPO road shows in Japan and the U.S and presentations to obtain corporate partners, including Schering-Plough and Kyowa Hakko. Dr. Lewis received a B.A. with Special Honors in Psychology from the George Washington University and an M.A. and Ph.D. in Psychology from Clark University in 1977, followed by postdoctoral training in Neurosciences at the University of Cambridge, postdoctoral training in Pharmacology at the National Institutes of Health and the University of Michigan.