Dr. Cesare Orlandi, M.D., F.A.C.C. F.E.S.C., has been the Chief Medical Officer at Lantheus Holdings, Inc. since joining in March 6, 2013. Dr. Orlandi has been the Chief Medical Officer at Lantheus Medical Imaging, Inc. since March 6, 2013. He is responsible for leading Clinical Development, Medical Affairs, Pharmacovigilence and Regulatory Affairs for Lantheus Medical, including its Phase 3 clinical trial program for flurpiridaz F 18. From January 2012 to February 2013, he served as Senior Vice President and Chief Medical Officer of TransTech Pharma, Inc., where he led drug development from Phase 1 through Phase 3 trials for the company's pipeline programs. Prior to joining TransTech in January 2012, he served as Senior Vice President of Clinical Development and Chief Medical Officer of Cardiokine, Inc. from 2007 to 2011. He was responsible for the development, submission and regulatory approval of several compounds in the cardiovascular area. Dr. Orlandi has more than 20 years of diverse pharmaceutical industry experience with a proven track record of directing successful drug development programs, providing leadership in product pipeline portfolio management and overseeing interactions with regulatory agencies. Prior to joining Cardiokine, Dr. Orlandi was Vice President, Global Clinical Development at Otsuka Pharmaceuticals from 1998 to 2007, where he was responsible for a variety of programs including tolvaptan, a vasopressin receptor antagonist. He has also held the Vice President, Research & Development position with Medco Research, Inc., in Research Triangle Park, NC; Medical Director and Principal Investigator, Nuclear Cardiology positions with The DuPont Merck Pharmaceutical Company in North Billerica, MA; and was a visiting scientist with the Upjohn Company in Kalamazoo, MI. He is licensed and board certified in cardiology in Italy, where he served as Staff Physician in the Department of Internal Medicine, Ospedale S. Matteo and University of Pavia Medical School, Pavia, Italy. Dr. Orlandi has also held academic and hospital appointments at Harvard Medical School and Brigham and Women's Hospital in Boston, MA. He worked with the Radiopharmaceutical Division of Du Pont Merck Pharmaceutical Company, which is now Lantheus Medical Imaging. He is an Adjunct Assistant Professor of Medicine at Tufts University School of Medicine, Boston. He is a founding member of the American Society of Nuclear Cardiology (ASNC), a Fellow of the American College of Cardiology (ACC), European Society of Cardiology (ESC) and American College of Angiology (ACA). He is also a member of the ESC Industry Panel. He has also published an extensive number of original articles, reviews, books and abstracts. Dr. Orlandi received his M.D. with honors from the University of Pavia Medical School, Pavia, Italy.