John T. Curnutte M.D., Ph.D.
Executive Vice President of Research and Development
Dr. John T. Curnutte, M.D., Ph.D., has been an Executive Vice President of Research & Development at Portola Pharmaceuticals, Inc. since February 2011. At Portola, Dr. Curnutte oversees all of it's R&D operations, including discovery research, development, clinical operations and regulatory affairs. Dr. Curnutte served as Chief Executive Officer of 3-V Biosciences, Inc. He served as President of Schering-Plough Biopharma, a unit of Schering-plough Corp. since June 1, 2005. Dr. Curnutte joined Schering-Plough Biopharma (formerly DNAX Research Institute) from Genentech, where he directed the activities of immunology, pathology and antibody technology and made significant contributions to the development of therapeutic and research monoclonal antibodies. He served as Senior Director of Genentech Inc. Devoting more than 30 years of his life to understanding the normal and abnormal functions of the immune system, Dr. Curnutte has helped hundreds of children and their families fight CGD-related infections and significantly improve the outlook of this progressive and often fatal disease. This is evident in his pro bono medical practice, which allows him to consult with patients, physicians and genetic counselors throughout the U.S. and Canada. Offering his time as a gift to the field of medicine, Dr. Curnutte facilitates cell and DNA testing for CGD families across the country. Specializing in pediatric hematology and oncology, he continues to serves as a medical staff member at Stanford University Medical Center and as an Adjunct Clinical Professor of Pediatrics at Stanford University School of Medicine. After serving on the faculty of the University of Michigan in Ann Arbor, Dr. Curnutte began focusing his research and clinical practice on immune deficiencies involving white blood cells. Intrigued by the potential of combining basic science with clinical medicine, he continued to integrate his scientific training in biochemistry with faculty, clinical and corporate posts at The Scripps Research Institute, the Lucile Salter Packard Children's Hospital at Stanford and Genentech. During this time, he was drawn to work with children who have cancer and blood diseases and he soon narrowed his focus on chronic granulomatous disease (CGD), an inherited disorder of the neutrophil function. He has been an Independent Director of diaDexus, Inc., since February 24, 2015. He has been Director of Pliant Therapeutics, Inc. since September 26, 2017. He served as a Director at 3-V Biosciences, Inc. Dr. Curnutte received his Ph.D. degree in biological chemistry and M.D. from Harvard Medical School. He holds an A.B. in biochemistry and molecular biology from Harvard University. He did his postdoctoral training in pediatrics (Massachusetts General Hospital) and pediatric hematology/oncology (Boston Children's Hospital and the Dana-Farber Cancer Institute).