Dr. Ulrich H. von Andrian, M.D., Ph.D. has been an Advisor of PureTech Health plc since October 13, 2016. Dr. von Andrian-Werburg has been the Mallinckrodt Professor of Immunopathology at Harvard Medical School since 2011. Dr. von Andrian served as Edward Mallinckrodt Jr. Professor of Immunopathology at Harvard Medical School since 2006. During the past 26+ years, he has been conducting basic research in immunology using a broad range of molecular, cellular and whole animal approaches. A major scientific focus has been on the molecular mechanisms of immune cell migration and homing in lymphoid and non-lymphoid tissues using intravital microscopy techniques. He has knowledge of basic exploration of immune responses to exogenous and endogenous challenges such as infections, tumors and immune diseases. Using in vivo microscopic imaging technologies developed in his laboratory, Dr. von Andrian has identified how different immune cells migrate and communicate in living tissues and how immunomodulatory drugs can be designed to control and modify these events. He co-founded Selecta Biosciences to apply these insights to the development of rationally engineered immunobiologics for the treatment and prevention of human diseases. Dr. von Andrian is the Co-Founder of Selecta Biosciences, Inc. and serves as its Co-Chair of the Scientific Advisory Board. He has been a Member of Scientific Advisory Board at Morphic Rock Therapeutic, Inc. since 2006. He serves as Member of Scientific Advisory Board at Moderna Therapeutics, Inc. He serves as Member of Scientific Advisory Council at Cancer Research Institute, Inc. He serves as Member of Scientific Advisory Board at Tarveda Therapeutics, Inc. (formerly Blend Therapeutics, Inc.). He served as Member of Scientific Advisory Board at DNIB Unwind, Inc. He has been Program Leader, Basic Immunology and Member, Steering Committee, Ragon Institute at MGH, MIT and Harvard, Cambridge, MA since 2013. Dr. von Andrian is a Member of the European Academy of Sciences and several professional societies from which he has received awards for outstanding research, including the Amgen Outstanding Investigator Award, the Henry Pickering Bowditch Award, the BD Biosciences Investigator Award and the Eugene Landis Award. From 1988 to 1989, he was Internship, Dept. of Surgery, Zentralklinikum Augsburg, Germany; Dept. of Neurology, Univ. of Michigan, Ann Arbor, MI; and Medizinische Klinik I, Klinikum Gro???hadern, Munich, Germany. He was a Visiting Scholar, Dept. of Applied Mechanics and Engineering Sciences, UCSD, La Jolla, CA from 1989 to 1992. From 1994 to 1999, he was Assistant Professor of Pathology, Harvard Medical School and Junior Investigator at CBR Institute for Biomedical Research, Boston, MA. From 1999 to 2003, he was Associate Professor of Pathology, Harvard Medical School and Investigator at CBRI. From 2003 to 2011, he was Professor of Pathology at Harvard Medical School and Senior Investigator at CBRI. He was a Postdoctoral Fellow at La Jolla Institute for Experimental Medicine, La Jolla, CA from 1989 to 1992. He has been on the Editorial Boards of Journal of Experimental Medicine since 2002, Faculty of 1000 since 2003, Current Immunology Reviews since 2004, Associate Editor, Immunity since 2005, Journal of Vascular Research since 2007, The Open Microbiology Journal since 2007, The Year in Immunology (NY Academy of Sciences) since 2007 and Cell since 2009. He served on the Editorial Boards of Microcirculation from 1999 to 2004, American Journal of Physiology: Heart and Circulatory Physiology from 1999 to 2000 and Board of Reviewing Editors, Science from 2008 to 2010. He has been a Member of Microcirculatory Society (MCS) since 1994, American Association of Immunologists (AAI) since 1998, North American Vascular Biology Organization (NAVBO) since 1998, Elected Member of American Association of University Pathologists (Pluto Society) since 2000, American Society for Investigative Pathology (ASIP) since 2002, Elected Member of European Academy of Sciences since 2002, The American Society for Cell Biology (ASCB) since 2004 and American Physiological Society (APS) since 2005. His postdoctoral research involved the development of intravital microscopy techniques that led to the discovery of the multi-step leukocyte adhesion cascade in vivo. After a second postdoctoral fellowship in the laboratory of Dr. Eugene C. Butcher at Stanford University from 1992 to 1993, Dr. von Andrian joined the Faculty of Harvard Medical School in 1994. He holds an M.D. from Ludwig-Maximillians University (Germany) in 1989, where he also conducted doctorate research on blood-brain barrier dysfunction following brain injury. He received Phd in Neurology/Neurosurgery from Ludwig-Maximilians Univ. Munich, Germany in 1992.