J. Fraser Wright Ph.D. — Scientific Co-Founder and Chief Technology Officer at Spark Therapeutics

Dr. J. Fraser Wright, Ph.D. serves as Scientific Co-Founder at Spark Therapeutics, Inc. and has been its Chief Technology Officer since January 5, 2015. Dr. Wright serves as Director of the Clinical Vector Core Laboratory at The Children's Hospital of Philadelphia. He served as Chief Technology Advisor at Spark Therapeutics, Inc. (a/k/a, Spark Therapeutics, LLC) until July 2013. He is also an Associate Professor of pathology and laboratory medicine at the University of Pennsylvania. Dr. Fraser has led efforts in basic research, process and analytical methods development and GMP manufacturing and quality systems supporting translational research. He has overseen investigational product chemistry, manufacturing and controls for gene therapy vectors administered to more than 100 human subjects in 12 clinical studies. His primary research interests focus on the development and clinical translation of gene therapy vectors with the goal of achieving effective new treatments for serious human diseases. With basic training in biochemistry, immunology and virology, he has been engaged for more than 20 years in the development of viral vector-based new biologic products in both industry and academic settings and previously served as director of development and clinical manufacturing at Avigen, Inc. He received his B.S. and Ph.D. in biochemistry from the University of Toronto.