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Everything as there is no transparency or stability
Incompetent and toxic leadership that has stayed in place despite many complaints to HR. There is no way to make the company profitable in the long term due to the strategy and diminishing talent. J&J brings the same old pharma leaders and expects different results.
No sense of direction. CEO is frequenlty absent and confused when present.
Fire them and start over
Stop thinking about the business only and start thinking about the people.