The PIs are generally knowledgeable and very enthusiastic about science
Honest, consistent communication and transparency. Stop allowing dept heads to create silos (their own "kingdoms"). HR leadership approaches role as one of protecting the Lab from its employees. No focus on employee development at the institutional level, esp for non-scientific staff.
Senior leadership needs to see administrative functions (HR, Communications, Finance, etc) as potential areas for building a true world-class place to work and do science, and then support great leaders in these areas and get rid of those who are just protecting their turf.