


Diverse employees at Karyopharm Therapeutics have rated Team, Happiness, and Compensation as the highest categories they have scored
Women at Karyopharm Therapeutics have rated Compensation, Team, and Happiness as the highest categories they have scored
Karyopharm Therapeutics employees are 10% more likely to recommend Karyopharm Therapeutics as a great place to work
| 38% | Promoters |
|---|---|
| 34% | Passives |
| 28% | Detractors |
Working at Karyopharm Therapeutics is rated highly by 90 employees, across various culture dimensions. Karyopharm Therapeutics employees are most satisfied about CEO Rating, Compensation, and Happiness categories, putting Karyopharm Therapeutics’s culture in the Top 15% compared to similar sized companies on Comparably and in the Top 25% compared to other companies in Boston. See below in detail how working at Karyopharm Therapeutics was rated by employees.
Overall Company Culture at Karyopharm Therapeutics is rated A-
Last updated months ago
Karyopharm Therapeutics ranks in the Top 15% of other companies on Comparably with 201-500 Employees for Overall Company Culture Score
Out of 504 Karyopharm Therapeutics employee reviews, 94% were positive. The remaining 6% were constructive reviews with the goal of helping Karyopharm Therapeutics improve their work culture.
| Positive Reviews | 94% |
|---|---|
| Constructive Feedback | 6% |
What is the best part about your compensation package?The salary is the best part of the compensation package.
What is most positive about the culture and environment at your company?Alignment to the key priorities, the four core programs.
What do you like best about the leadership team?The ET has the best interest of the company in mind, aligned with the key priorities.
What do your coworkers need to improve and how could you work together better?Open mind. Willingness to take ownership/
Why do you feel undervalued and what would make you feel better about your compensation?seeing others who do less than me get promoted over me doesn't make me want to work harder, especially when that someone dumps their work on me
What's going wrong and how can it be improved?We need to focus more on structure and process
Karyopharm is an innovation-driven pharmaceutical company whose core technology leverages the inhibition of nuclear export as a mechanism to treat patients with cancer and other medical conditions
Karyopharm Therapeutics was founded in 2008 and its current CEO is Richard Paulson. Since its inception 18 years ago, Karyopharm Therapeutics has grown to 400 employees.
We seek to foster scientific creativity with pioneering technologies and developmental approaches within an innovative culture that will accelerate first-in-class small molecule modulators of nuclear transport into effective therapeutics for life-threatening conditions. At Karyopharm, we support a culture of innovation, courage, urgency, resiliency and energy with our employees and collaborators. Integrity and respect are core to our success.
Karyopharm Therapeutics Inc. is an innovation-driven pharmaceutical company focused on discovery and development of novel first-in-class drugs directed against nuclear transport and related targets for the treatment of cancer and other major diseases.
| Website | www.karyopharm.com |
|---|---|
| Founding Date | 2008 |
| Tel | +1 (617) 658-0600 |
| Company Status | Public |
| Stock | KPTI |
| Jobs | www.karyopharm.com/about/careers/ |
| Social Sites | |
| Headquarters | |
| Newton HQ | Newton, MA 02459 United States of America |
| Additional HQ | 94 Yigal Alon St Tel Aviv District Israel |









Karyopharm Therapeutics has 400 employees in 2 locations. 90 employees at Karyopharm Therapeutics have reviewed Karyopharm Therapeutics across various culture dimensions, providing their opinions on items ranging from executive ratings to the pace at work. The latest review was months ago.
Overall, the 90 Karyopharm Therapeutics employees give their leadership a grade of A, or Top 10% of similar size companies on Comparably. This includes specific ratings of their executive team, CEO, and manager.
Employees at Karyopharm Therapeutics are extremely happy with their total compensation at Karyopharm Therapeutics, which includes a combination of pay, stock and equity, and benefits.
Overall, employees at Karyopharm Therapeutics are extremely happy with their team. 90 Participants grade the quality of their coworkers an A. The majority believe the meetings at Karyopharm Therapeutics are effective, and the majority look forward to interacting with their coworkers.
The majority of employees at Karyopharm Therapeutics believe the environment at Karyopharm Therapeutics is positive. Most Participants believe the pace of work at Karyopharm Therapeutics is comfortably fast. About 41% of the employees at Karyopharm Therapeutics work 8 hours or less, while 7% of them have an extremely long day - longer than twelve hours.
Overall, the employees at Karyopharm Therapeutics are happy, based on their aggregated ratings of future outlook, customer perception, and their excitement going to work.


The prevailing opinion from Comparably users in Boston about their company is that it was very prepared on their first day. Boston employees concluded that their overall onboarding experience was positive. 75% said their direct manager was helpful with their acclimation during the first 90 days. First impressions are important, and how prepared a company is on your first day leaves a lasting impression.
Employees’ understanding of Karyopharm Therapeutics' KPIs and OKRs is essential for its success. Out of 88 Karyopharm Therapeutics employees who’ve answered, “Are your company’s goals clear and are you invested in them?” 81 have said yes.
Karyopharm Therapeutics’s CEO Richard Paulson started in this role in 2021. Richard’s approval rate is in the Top 5% of all CEOs of similar-sized companies on Comparably, and in the Top 10% compared to the CEOs of all other companies in Boston. Karyopharm Therapeutics’s CEO is highly regarded especially by employees in the IT department, employees with Entry Level experience, and employees in the Sales department. However, employees in the Finance department, Asian or Pacific Islander employees, and employees in the Legal department have a less favorable view of the CEO and believe there is room for improvement. Compared to Karyopharm Therapeutics’s competitors, Richard Paulson ranks right above Amgen CEO Robert Bradway. Under Paulson’s leadership, Karyopharm Therapeutics employee respondents are most happy about their Compensation and the company’s Happiness. eNPS and Meetings are two areas, according to respondents, where Karyopharm Therapeutics could stand to see real improvement.
The Karyopharm Therapeutics Executive Team is rated an “A-” and led by CEO Richard Paulson, Co-Founder, Co-Chairman of Scientific Advisory Board, President & Chief Scientific Officer Sharon Shacham Ph.D., M.B.A., and Chief Development Operations Officer Ran Frenkel
Richard Paulson CEO / President
Mr. Paulson was appointed President and Chief Executive Officer of Karyopharm in May 2021 and has served as a member of... read more
Sharon Shacham Ph.D., M.B.A. Co-Founder, Co-Chairman of Scientific Advisory Board, President & Chief Scientific Officer
Dr. Sharon Shacham, Ph.D., MBA, Co-Founded Karyopharm Therapeutics Inc. in 2008 and has been its Chief Scientific... read more
Ran Frenkel Chief Development Operations Officer
Ran Frenkel serves as the Chief Development Operations Officer of Karyopharm Therapeutics Inc.. Ran started at... read more
Yosef Landesman Senior Director, Head of Biology and Scientific Affairs
Yosef Landesman serves as the Senior Director, Head of Biology and Scientific Affairs of Karyopharm Therapeutics Inc..... read more
Brian Austad Senior Vice President, Pharmaceutical Sciences and Vendor Management
Brian Austad serves as the Senior Vice President, Pharmaceutical Sciences and Vendor Management of Karyopharm... read more
Jatin Shah SVP Clinical Development
Jatin Shah serves as the SVP Clinical Development of Karyopharm Therapeutics Inc.. Jatin started at Karyopharm... read more
Chris Primiano SVP, Corporate Development, General Counsel & Secretary
Chris Primiano serves as the SVP, Corporate Development, General Counsel & Secretary of Karyopharm Therapeutics Inc..... read more
Kristan Gallitano Vice President, Data Management
Kristan Gallitano serves as the Vice President, Data Management of Karyopharm Therapeutics Inc.. Kristan started at... read more
Cameron Peters VP Finance
Cameron Peters serves as the VP Finance of Karyopharm Therapeutics Inc.. Cameron started at Karyopharm Therapeutics Inc.... read more
How much do people at Karyopharm Therapeutics get paid? See the latest salaries by department and job title. The average estimated annual salary, including base and bonus, at Karyopharm Therapeutics is $98,067, or $47 per hour, while the estimated median salary is $94,268, or $45 per hour.
At Karyopharm Therapeutics, the highest paid job is a General Counsel at $281,190 annually and the lowest is a CS Rep at $44,885 annually. Average Karyopharm Therapeutics salaries by department include: Finance at $64,304, Engineering at $116,152, Marketing at $184,278, and Customer Support at $61,489. Half of Karyopharm Therapeutics salaries are above $94,268.
90 employees at Karyopharm Therapeutics rank their Compensation in the Top 5% of similar sized companies in the US (based on 183 ratings) while 90 employees at Karyopharm Therapeutics rank their Perks And Benefits in the Top 5% of similar sized companies in the US (based on 187 ratings).
Last updated months ago.
| Summary | Salary Range | Percentile |
|---|---|---|
1st Percentile $58k | $58k | 1st Percentile |
17th Percentile $78k | $78k | 17th Percentile |
33rd Percentile $93k | $93k | 33rd Percentile |
50th Percentile $178k | $178k | 50th Percentile |
67th Percentile $277k | $277k | 67th Percentile |
83rd Percentile $319k | $319k | 83rd Percentile |
100th Percentile $369k | $369k | 100th Percentile |
* Estimated salaries Estimated salaries are based on data provided anonymously by employees and/or estimated by other statistical methods.
Diverse employees at Karyopharm Therapeutics score the company 76/100 across various culture categories, placing Karyopharm Therapeutics in the Top 30% of companies on Comparably with 201-500 Employees for Comparably's diversity score. The Diversity score provides insights into how diverse employees feel and rate their work experience at Karyopharm Therapeutics across various culture dimensions.
At Karyopharm, we pride ourselves in diversity and inclusion with more than fifty percent of our employees being female, a workforce that speaks over twenty languages, and a diverse management team.,,Karyopharm is committed to improving the lives of patients and those who love them by developing novel therapies to treat cancer and other rare diseases. The work we do is both inspiring and life-changing. It requires the most diverse,the most unique, and the most authentic team in the industry. Karyopharmers are extremely innovative and we think differently. We are so proud of our global team who bring their broad range of expertise, experiences, languages, and backgrounds with them every day to do the work that is so clearly their passion. We are committed to diversity, equity, inclusion and belonging. We celebrate all forms of diversity (e.g. gender, gender identity, race, ethnicity, national origin, sexual orientation, differently-abled, veterans and so much more). It is our firm belief that this is a part of our strength and makes us uniquely suited to succeed in our ongoing commitment to employees, physicians, patients, and families alike.
• 401k with competitive match and immediate vesting • Employee Stock Purchase Plan with 15% discount • Stock options vest at 25% on the first anniversary of hire date and monthly for the next 36 months • Generous PTO program • Monthly cell phone allowance for all employees • Employee recognition awards including cash compensation and equity • Free gym on-site and fitness reimbursement program
Karyopharm Therapeutics' PTO and Vacation policy typically gives 15-20 days off a year.

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In 2019, Karyopharm Therapeutics applied for 15 H1B visas. Of the work permits applied for, 100% were approved.
Karyopharm Therapeutics has a total of 400 employees
H1B Applications Outcome
This data was calculated using publicly sourced data from OFLC Performance Data

Candidates By Department
All Industries | 78% | |
|---|---|---|
Marketing | 11% | |
HR | 11% |
Candidates By Location
Boston | 78% | |
|---|---|---|
Mount Laurel | 11% | |
Other | 11% |
Who is the CEO of Karyopharm Therapeutics?
Karyopharm Therapeutics CEO is Richard Paulson, their score by employees is 82
What is Karyopharm Therapeutics eNPS?
The eNPS for Karyopharm Therapeutics is 10
What is the salary for Account Executive in Karyopharm Therapeutics?
Account Executive average salary in the US is 119k
What are the salaries in the Product in Karyopharm Therapeutics?
The average salaries for Product in Karyopharm Therapeutics is 138k
How many employees work in Karyopharm Therapeutics?
Karyopharm Therapeutics has 400 employees